PLK1 anticorps (pThr210)

N° du produit ABIN5688913

L’anticorps Lapin Polyclonal anti-PLK1 a été validé pour WB. Il convient pour détecter PLK1 dans des échantillons de Humain, Souris, Rat, Xenopus laevis, Boeuf (Vache), Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour PLK1 anticorps (pThr210) (ABIN5688913)

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivité: Humain, Souris, Rat, Xenopus laevis, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PLK1 anticorps

Épitope: pThr210

Purification: Affinity Purified

Immunogène: Phosphopeptide corresponding to amino acid residues surrounding the phospho-Thr210 of PLK1.

Information d'application

Indications d'application: The antibody has been directly tested for reactivity in Western blots in rat and human tissues. It is anticipated that the antibody will react with bovine, canine, mouse, non-human primate, Xenopus and Zebrafish tissues based on the fact that these species have 100 % homology with the amino acid sequence used as antigen.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 μLin 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per mL BSA and 50 % glycerol.

Stock: -20 °C

Stockage commentaire: PLK1 antibody can be stored at -20°C and is stable at -20°C for at least 1 year.

Détails sur PLK1

Antigène: PLK1 (Polo-Like Kinase 1 (PLK1))

Autre désignation: PLK1

Sujet: Polo-like kinases are important regulators of cell cycle progression. PLK1 is a highly conserved Ser/Thr kinase that has essential roles in the formation of mitotic bipolar spindles (van Vugt et al., 2004). Deregulated expression of PLK's is detected in many types of cancer and associated with oncogenesis (Takei et al., 2005). It has been proposed that PLK1 function is altered at different stages of mitosis through consecutive phosphorylation events at Ser137 and Thr210 (van de Weerdt et al., 2005).

Poids moléculaire: 66 kDa

ID gène: 5347

UniProt: P53350

Pathways: Cycle Cellulaire, M Phase